| 5 Nov | Ark Pine Bluff 41 | at | South Florida 70 | vs SWAC | ||
| 10 Nov | Boston College 74 | at | South Florida 60 | vs ACC | ||
| 13 Nov | IUPUI 70 | at | South Florida 53 | vs HL | ||
| 21 Nov | Wofford 55 | at | South Florida 69 | vs SC | ||
| 25 Nov | South Florida 66 | vs | Loyola-Chicago 55 | George Town, Cayman Islands | vs MVC | |
| 26 Nov | New Mexico St 65 | vs | South Florida 45 | George Town, CAY | vs WAC | |
| 27 Nov | Nebraska 74 | vs | South Florida 67 | George Town, CAY | vs B10 | |
| 2 Dec | Furman 55 | at | South Florida 65 | vs SC | ||
| 6 Dec | Dartmouth 44 | at | South Florida 63 | vs Ivy | ||
| 15 Dec | Drexel 61 | at | South Florida 81 | vs CAA | ||
| 18 Dec | Utah St 76 | vs | South Florida 74 | OT | Houston, TX | vs MWC |
| 21 Dec | Florida St 66 | vs | South Florida 60 | Sunrise, FL | vs ACC | |
| 29 Dec | FL Atlantic 58 | at | South Florida 60 | vs CUSA | ||
| 1 Jan | South Florida 64 | at | SMU 82 | |||
| 4 Jan | Connecticut 60 | at | South Florida 75 | |||
| 7 Jan | South Florida 59 | at | East Carolina 62 | |||
| 12 Jan | Memphis 68 | at | South Florida 64 | |||
| 18 Jan | South Florida | at | UCF | |||
| 21 Jan | Wichita St | at | South Florida | |||
| 26 Jan | South Florida | at | Houston | |||
| 29 Jan | South Florida | at | Tulane | |||
| 1 Feb | UCF | at | South Florida | |||
| 8 Feb | South Florida | at | Memphis | |||
| 12 Feb | Houston | at | South Florida | |||
| 15 Feb | Tulsa | at | South Florida | |||
| 20 Feb | South Florida | at | Wichita St | |||
| 23 Feb | South Florida | at | Connecticut | |||
| 26 Feb | East Carolina | at | South Florida | |||
| 1 Mar | South Florida | at | Temple | |||
| 3 Mar | Cincinnati | at | South Florida | |||
| 7 Mar | SMU | at | South Florida |
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